CJC-1295 with DAC - Peptide Information
- Chemical Name: Tetrasubstituted GRF (1-29) with Drug Affinity Complex (DAC)
- Format: Lyophilised Powder (Vial)
- Concentration: Available in 2mg, 5mg, and 10mg variants
- Inclusions: Includes 1 x 3ml vial of Bacteriostatic Water (solvent for reconstitution)
- Purity: High Purity (>98%)
- Grade: Research Grade (Not for Human Consumption)
Product Overview
CJC-1295 with DAC is a long-acting synthetic analogue of Growth Hormone Releasing Hormone (GHRH). It distinguishes itself from standard GHRH analogues through the addition of a Drug Affinity Complex (DAC) specifically designed to bind to serum albumin.
This product is strictly intended for laboratory research and in vitro use only. It is not a medicine, food, or cosmetic product and is not intended for human consumption or injection.
Research Mechanism and Applications
In laboratory settings, CJC-1295 with DAC is a primary subject of interest for researchers studying peptide stability and half-life extension technologies. The addition of the DAC (maleimidopropionic acid) enables the peptide to form a covalent bond with albumin after introduction into a substrate.
Key areas of biochemical investigation include:
- Albumin Conjugation: Researchers study the bioconjugation process where the reactive chemical linker binds to serum albumin, protecting the peptide from enzymatic degradation.
- Extended Pharmacokinetics: Unlike "No DAC" variants which mimic natural pulsatile spikes, CJC-1295 with DAC is used to observe the effects of continuous, low-level GHRH receptor stimulation over prolonged periods (often several days in animal models).
- GHRH Receptor Agonism: The peptide retains high affinity for the GHRH receptor, and studies focus on the downstream effects of sustained receptor activation versus pulsatile activation.
Quality and Purity
We adhere to stringent manufacturing standards to provide researchers with a consistent and reliable product.
- Rigorous Testing: This product possesses a purity of >98% as verified via High-Performance Liquid Chromatography (HPLC).
- Molecular Verification: The molecular mass has been confirmed via Mass Spectrometry (MS).
- Contaminant Free: This product has been rigorously tested and confirmed to be free from heavy metals and bacterial contaminants.
- Solvent Included: Each order includes a 3ml vial of Bacteriostatic Water containing 0.9% Benzyl Alcohol, provided strictly as a solvent for laboratory reconstitution and solubility testing.
Safety and Handling
WARNING: This product is a research chemical.
- Keep out of reach of children.
- Not for human use. This product is not a dietary supplement or drug.
- Store in a cool, dry place away from direct sunlight.
Please refer to our 'Storage and Reconstitution' section for instructions on maintaining optimal product integrity and results.
Scientific References
For further reading on the biochemical properties, albumin binding mechanics, and research studies regarding CJC-1295, please refer to the following literature:
Journal of Clinical Endocrinology & Metabolism (2006) – Research on the prolonged activity and pharmacokinetics of CJC-1295. click here to view the article
Drug Design, Development and Therapy (2015) – Analysis of GHRH analogs and the impact of half-life extension technologies. click here to view the article
Basic & Clinical Pharmacology & Toxicology (2009) – Study on the stability and interactions of albumin-binding peptides. click here to view the article
