GHK-Cu (Copper Peptide) | 50mg & 100mg
Technical Specifications
- Sequence: Gly-His-Lys (Copper Complex)
- Chemical Name: Copper Tripeptide-1
- Format: Lyophilised Cake/Powder
- Appearance: Deep Blue / Azure Crystal (Characteristic of Copper binding)
- Purity: >99% (HPLC Verified)
- Copper Content: Stoichiometrically balanced (1:1 Complex)
- Solubility: Extremely High (Aqueous)
- Solvent: Solvent not included (Sold Separately)
- Grade: Analytical Research Grade
Variant Breakdown
- 50mg Vial: Standard High-Potency Vial.
- 100mg Vial: Ultra-High Density Vial.
- Vial Capacity: 3ml.
- Note: The 100mg variant contains a significant amount of peptide. The resulting solution will be a very dark, concentrated blue.
Product Overview
GHK-Cu is a naturally occurring copper complex of the tripeptide Glycyl-L-Histidyl-L-Lysine.
The "Blue" Marker of Authenticity:
Unlike almost all other research peptides, which are white powders, GHK-Cu is distinctive for its vibrant blue colour. This hue is not a dye; it is the physical evidence of the copper ion (Cu2+) being complexed within the peptide structure.
Originally isolated from human plasma in the 1970s, GHK-Cu is chemically distinct because it acts as a feedback signal for tissue remodeling. Research indicates that the peptide facilitates the uptake of copper into cells—a trace element vital for the enzymatic function of lysyl oxidase (required for collagen cross-linking). Consequently, GHK-Cu is the primary reagent used to investigate skin regeneration, collagen synthesis (Types I & III), and the down-regulation of inflammatory cytokines.
Quality Assurance
This compound has undergone rigorous third-party analysis.
- HPLC Verified: Independent analysis confirms peptide purity exceeds 99%.
- Copper Chelation: Verified to ensure the peptide is fully complexed with copper (giving it the blue colour) rather than a simple mix of peptide and copper salts.
- TFA Removal: Processed to remove inflammatory salts.
Research Mechanism
In laboratory settings, GHK-Cu is utilised to investigate:
- ECM Remodeling: The balance between breaking down old, damaged collagen (via metalloproteinases) and synthesising new, healthy connective tissue.
- Fibroblast Activation: Researching the acceleration of wound healing and the "youthful" gene expression patterns in aged fibroblasts.
- Stem Cell Potential: Studies examining the peptide's ability to restore the proliferative potential of epidermal stem cells (p63 marker).
- Anti-Inflammation: Reducing oxidative stress and suppressing pro-inflammatory molecules like TNF-alpha and IL-6.
Safety and Handling
WARNING: This product is exclusively for laboratory research and in vitro use.
- Research Only: Not intended for human consumption, cosmetic application, or therapeutic use.
- Handling: Wear appropriate personal protective equipment (PPE).
Storage: Store lyophilised vials in a cool, dry place. For long-term preservation, freezing at -20°C is recommended.
Scientific References
Journal of Peptide Science (2018) – "GHK-Cu may prevent anxiety, pain, aggression and enlarge brain size." (Review of the systemic effects). View Article
Oxidative Medicine and Cellular Longevity (2012) – "The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging." (The major review by Loren Pickart). View Article
Wound Repair and Regeneration (2008) – "The effect of GHK-Cu on wound healing and scar formation." View Article
International Journal of Molecular Sciences (2018) – "Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data." View Article