SLU-PP-332 (ERRα Agonist) Information
- Chemical Name: SLU-PP-332
- Format: Lyophilised Powder (Vial)
- Concentration: Available in 5mg vial
- Purity: High Purity (>98%)
- Grade: Research Grade (Not for Human Consumption)
Product Overview
SLU-PP-332 is a novel, synthetic small molecule that functions as a selective agonist of the Estrogen-Related Receptor Alpha (ERRα). Unlike traditional ligands that target nuclear receptors, SLU-PP-332 is designed to enhance the constitutive activity of ERRα without binding to the estrogen receptor (ER).
This compound is currently a subject of intense investigation in the field of metabolic biology. It is distinct from other metabolic agents as it does not regulate appetite but rather influences the fundamental pathways of energy expenditure and substrate utilization at the cellular level.
This product is strictly intended for laboratory research and in vitro use only. It is not a medicine, food, or cosmetic product and is not intended for human consumption or injection.
Research Mechanism and Applications
In laboratory settings, SLU-PP-332 is utilized to investigate the transcriptional regulation of metabolic genes. By activating ERRα, the compound mimics the signaling pathways typically triggered by physiological stress or endurance activity.
Researchers utilizing this compound in controlled experimental models investigate the following biological mechanisms:
- Mitochondrial Biogenesis: SLU-PP-332 is used to study the upregulation of genes responsible for creating new mitochondria, facilitating research into cellular energy capacity and efficiency.
- Fatty Acid Oxidation: The compound allows researchers to observe the shift in cellular substrate preference, specifically the promotion of fatty acid oxidation (fat burning) over glucose utilization in skeletal muscle and adipose tissue models.
- Muscle Fiber Remodeling: Studies explore the compound's ability to influence the transformation of skeletal muscle fibers towards a more oxidative, endurance-type phenotype (Type I fibers).
Quality and Purity
We adhere to stringent manufacturing standards to provide researchers with a consistent and reliable product.
- Rigorous Testing: This product possesses a purity of >98% as verified via High-Performance Liquid Chromatography (HPLC).
- Molecular Verification: The molecular mass has been confirmed via Mass Spectrometry (MS).
- Contaminant Free: This product has been rigorously tested and confirmed to be free from heavy metals and bacterial contaminants.
Safety and Handling
WARNING: This product is a research chemical.
- Keep out of reach of children.
- Not for human use. This product is not a dietary supplement or drug.
- Store in a cool, dry place away from direct sunlight.
- Please refer to our 'Storage and Reconstitution' section for instructions on maintaining optimal product integrity and results.
Scientific References
For detailed data on the pharmacological profile, ERRα activation, and metabolic studies regarding SLU-PP-332, please refer to the following literature:
ACS Pharmacology & Translational Science (2021) – Investigation into the chemical structure and metabolic effects of synthetic ERRα agonists. click here to view the article
Journal of Pharmacology and Experimental Therapeutics (2023) – Research regarding the effect of SLU-PP-332 on mitochondrial function and endurance capacity in mice. click here to view the article
Trends in Pharmacological Sciences (2019) – Review of Estrogen-Related Receptors (ERRs) as therapeutic targets in metabolic research. click here to view the article
