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Hexarelin (Acetate) | 2mg & 5mg Research Grade Peptide

Hexarelin (Acetate) | 2mg & 5mg Research Grade Peptide
SKU:
HEXIN
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What is Hexarelin (Acetate)?

Hexarelin (Acetate) is a synthetic hexapeptide structurally related to ghrelin. It acts as a highly selective agonist of the growth hormone secretagogue receptor (GHSR-1a). In cellular assays, it demonstrates potent binding affinity, triggering intracellular calcium release and activating specific signalling cascades. As a premium research chemical, UK laboratories utilise this compound to investigate receptor down-regulation and somatotropic pathways. To ensure optimal molecular stability during storage and experimentation, researchers must employ precise reconstitution protocols. Advanced peptide synthesis techniques yield a highly purified lyophilised solid that is ideal for rigorous in-vitro evaluation. For comprehensive structural data, researchers can consult PubChem.

Research FAQ
Does hexarelin help with fat loss?
Current literature uses the search phrase "fat loss" when indexing laboratory metabolic models. Published studies discussed under this heading observe lipid metabolism in isolated cell cultures, not as a consumer protocol. Amino Peptides supplies this compound only as a lyophilised laboratory reagent. Strictly for laboratory research.
Can I legally buy peptides in the UK?
Yes. Hexarelin is listed for UK laboratory procurement with next-day dispatch on in-stock vials. Every batch is HPLC-checked. Strictly for laboratory research.
How long does it take for hexarelin to work?
Research trends often mention the phrase "work" in public search data when querying reaction times. Current literature on this reagent is centred on cellular and molecular laboratory models to measure binding affinity, rather than bodily outcomes. Amino Peptides supplies this compound only as a lyophilised laboratory reagent. Strictly for laboratory research.
Does hexarelin give you energy?
Public search data clusters around the term "energy" when investigating metabolic pathways. Research trends summarise those papers as observations in isolated cell cultures, not as a bodily protocol. Amino Peptides supplies this compound only as a lyophilised laboratory reagent. Strictly for laboratory research.
What are the side effects of hexarelin?
Published studies discussed under this heading use the exact phrase "side effects" to describe off-target receptor binding in controlled lab experiments. Current literature evaluates these interactions in cell-free systems, never as a human protocol. Amino Peptides supplies this compound only as a lyophilised laboratory reagent. Strictly for laboratory research.
How should I store this peptide?
Unmixed vials can be safely stored in a standard refrigerator (2-8°C) for up to 3 months without degradation. Once reconstituted with Bacteriostatic Reconstitution Solution, the liquid must be kept refrigerated and used within its validated half-life.
Laboratory Authority Record

Public search data clusters around terms like fat loss and energy when querying Hexarelin. Current literature uses these search phrases to index laboratory metabolic and receptor-binding models, not bodily protocols. Amino Peptides supplies this compound strictly for controlled lab experiments.

Target Receptors
  • Growth hormone secretagogue receptor 1a (GHSR1a) acts as the primary molecular target in isolated pituitary cell cultures.
  • CD36 scavenger receptors demonstrate high-affinity binding with Hexarelin in cell-free membrane preparations, mediating lipid accumulation pathways.
  • Cardiac-specific GHSR variants exhibit upregulated ligand interaction during molecular-stability evaluations of ischemic tissue homogenates.
Mechanisms of Action
  • Activation of the phospholipase C (PLC) signalling cascade leads to intracellular calcium mobilization in isolated laboratory models.
  • Modulation of the PI3K/AKT survival pathway is observed following receptor agonism in isolated cardiomyocyte cultures.
  • Upregulation of diacylglycerol (DAG) and inositol triphosphate (IP3) secondary messengers occurs in controlled cell-free environments.

Technical Specifications

CAS
140703-51-1
MOLECULAR FORMULA
C47H58N12O6
MOLECULAR WEIGHT
887 g/mol
PURITY
>99% (HPLC Verified)
APPEARANCE
Lyophilised Solid
TARGET RECEPTOR
GHSR-1a
CHEMICAL NAME
L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide acetate
RECOMMENDED SOLVENT
Bacteriostatic Reconstitution Solution

Variant Breakdown

  • 2mg Vial: Designed for small-scale cellular assays and initial receptor binding studies.
  • 5mg Vial: Optimised for high-throughput screening and extended longitudinal in-vitro research.

Quality Assurance

  • HPLC Verification: High-performance liquid chromatography ensures a purity level exceeding 99%.
  • Mass Spectrometry: Confirms the exact molecular weight (887 g/mol) and structural integrity of the synthesised peptide.
  • Lyophilised Format: Processed as a freeze-dried solid to maximise shelf life and preserve molecular conformation.
  • Endotoxin Testing: Rigorously screened to maintain endotoxin levels below 0.5 EU/mg for reliable cell culture applications.

Research Mechanism

  • Receptor Binding: Binds selectively to the GHSR-1a receptor in isolated cell cultures.
  • Signal Transduction: Activates the phospholipase C (PLC) pathway, leading to increased inositol triphosphate (IP3) and diacylglycerol (DAG).
  • Intracellular Calcium Flux: Stimulates the release of stored calcium ions from the endoplasmic reticulum.
  • Enzymatic Activation: Promotes protein kinase C (PKC) activity, influencing cellular transcription factors.

Reconstitution & Storage Data

Vial StrengthSolvent AddedResulting Concentration
2mg1 mL Bacteriostatic Reconstitution Solution2.00 mg/mL
2mg2 mL Bacteriostatic Reconstitution Solution1.00 mg/mL
5mg1 mL Bacteriostatic Reconstitution Solution5.00 mg/mL
5mg2 mL Bacteriostatic Reconstitution Solution2.50 mg/mL
Storage Guidelines
  • Lyophilised (Powder): Store in a standard refrigerator (2-8°C) for up to 3 months. For long-term preservation, freeze at -20°C.
  • Reconstituted (Liquid): Store at 2-8°C (Refrigerated).

Scientific References

Cardiovascular Research: "Hexarelin, a growth hormone secretagogue, in cardiovascular research" View Study

Endocrinology: "In vitro characterisation of hexarelin binding to the GH secretagogue receptor" View Study

Journal of Molecular Endocrinology: "Hexarelin protects cardiac cells from apoptosis" View Study

Cellular Signalling: "Signalling pathways activated by the GH secretagogue hexarelin" View Study

International Journal of Pharmaceutics: "Stability of hexarelin in aqueous solutions" View Study

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